Sphingosine-1-phosphate receptor modulator
UC in adults
Active malignancy; heart failure, stroke or unstable angina in previous six months; immunodeficiency. Use with caution in elderly patients; cerebrovascular disease; chronic obstructive pulmonary disease; severe respiratory disease; severe sleep aponoea; diabetes; uncontrolled high blood pressure; retinal disease; uveitis. Avoid during pregnancy and breasteeding and in severe hepatic impairment. | Potential side effects: Slow heartbeat; headache; high blood pressure/cholesterol; low white blood cell count; cystitis; dizziness
Oral tablet
Dose: 2mg once daily, with food for first 3 days, then with or without food; if treatment interrupted for more than 7 days, resume with food for first 3 days
2mg (28) tablets