Sulfasalazine (Salazopyrin)

Pfizer

Description

Aminosalicylate

Indications

Acute attacks of mild-to-moderate and severe UC and active CD in adults; maintenance of remission of UC in adults

Contraindications

Asthma; acute porphyrias; glucose-6-phosphate dehydrogenase (G6PD) deficiency; severe renal impairment. Risk of haematological and hepatic toxicity (usually in first 3-6 months); treatment should be discontinued. | Potential side effects: Joint pain; cough; diarrhoea; dizziness; fever; gastrointestinal discomfort; headache; low white blood cell count; nausea; skin reactions; vomiting; insomnia; tinnitus; urine abnormalities; mouth ulcers; altered taste

Preparations Available

Oral tablet/suspension; suppository

Quantity

Dose: Oral 1–2.4g four times daily in acute attacks until remission, then 500mg four times daily. Rectal 0.5–1g twice daily, alone or in conjection with oral therapy

Sizes Available

500mg suppository (10), £3.30; generic: 500mg tablets (112), £55.59; 500mg gastro-resistant tablets (112), £62.66; 250g/5ml oral suspension (500), £125.00; 500mg suppositories (10), £3.30

Price

500mg suppository (10), £3.30; generic: 500mg tablets (112), £55.59; 500mg gastro-resistant tablets (112), £62.66; 250g/5ml oral suspension (500), £125.00; 500mg suppositories (10), £3.30

More on: Aminosalicylates