Mercaptopurine (Hanoxil)

Indications

Maintenance of remission of CD and UC in adults and children 2–17 years old. Monitor blood tests as per local/national guidelines.

Contraindications

Caution in hepatic or renal impairment or reduced thiopurine methyltransferase (TPMT) activity (measure before starting treatment). Avoid in pregnancy and discontinue while breastfeeding. | Potential side effects: Anaemia; reduced appetite; bone marrow depression; diarrhoea; hepatic disorders; hepatotoxicity (more common at high doses); low white blood cell and platelet count; oral disorders; pancreatitis; nausea; vomiting

Preparations Available

Oral tablet

Quantity

Dose: 1–1.5mg/kg daily

Sizes Available

50mg tablets (25), £10.70; generic: 10mg tablets (100), £621.39; 50mg (25), £10.50

Price

50mg tablets (25), £10.70; generic: 10mg tablets (100), £621.39; 50mg (25), £10.50

More on: Immunosuppressants